CD140b (PDGFRB), Biotin, clone: APB5, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-1402-80
Additional Details : Weight : 0.25000kg
DescriptionDescription: The APB5 monoclonal antibody reacts with the mouse CD140b molecule, the beta chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRb is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylates substrates. Dimers of PDGFR consist of either homodimers of alpha/alpha, beta/beta, or heterodimers of alpha/beta and serve as a substrate for its kinase activity. CD140b is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues. The PDGFR beta chain is reported to play a significant role in formation of fibrous atherosclerotic lesions.Applications Reported: The APB5 antibody has been reported for use in flow cytometric analysis.Applications Tested: The APB5 antibody has been tested by flow cytometric analysis of NIH/3T3 cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|PDGF Receptor beta, JTK12, PDGFR, PDGFR1, CD140 antigen-like family member B, PDGF-R-beta, beta-type platelet-derived growth factor receptor|
|IgG2a, kappa, kappa|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.