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CD142 Monoclonal Antibody (HTF-1), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-1429-42
Additional Details : Weight : 0.23750kg
Description
Description: This HTF-1 monoclonal antibody reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa. The HTF-1 antibody has been reported to exhibit blocking activity. Applications Reported: This HTF-1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This HTF-1 antibody has been pre-titrated and tested by flow cytometric analysis of LPS-stimulated normal human peripheral blood cells. This can be used at 5 μL (0.06 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.
CD142 Monoclonal antibody specifically detects CD142 in Human samples. It is validated for Flow Cytometry.Specifications
| CD142 | |
| Monoclonal | |
| 5 μL/Test | |
| PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
| P13726 | |
| F3 | |
| Affinity chromatography | |
| RUO | |
| 2152 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
| Flow Cytometry | |
| HTF-1 | |
| APC | |
| F3 | |
| AA409063; CD142; Cf3; Cf-3; Coagulation factor III; coagulation factor III (thromboplastin, tissue factor); coagulation factor III, tissue factor; F3; TF; TFA; Thromboplastin; Tissue factor | |
| Mouse | |
| 100 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
For Research Use Only.