CD142, Functional Grade, clone: HTF-1, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 16-1429-82
Additional Details : Weight : 0.09500kg
DescriptionFiltration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. This gene encodes coagulation factor III which is a cell surface glycoprotein. This factor enables cells to initiate the blood coagulation cascades, and it functions as the high-affinity receptor for the coagulation factor VII. The resulting complex provides a catalytic event that is responsible for initiation of the coagulation protease cascades by specific limited proteolysis. Unlike the other cofactors of these protease cascades, which circulate as nonfunctional precursors, this factor is a potent initiator that is fully functional when expressed on cell surfaces. There are 3 distinct domains of this factor: extracellular, transmembrane, and cytoplasmic. This protein is the only one in the coagulation pathway for which a congenital deficiency has not been described.
|PBS with no preservative; pH 7.2|
|F3, Coagulation factor 3, TF, TFA|
|Flow Cytometry, Functional Assay, Immunocytochemistry, Immunofluorescence, Western Blot|
For Research Use Only.