CD144 (VE-cadherin) Rat anti-Mouse, Clone: eBioBV14 (BV14), eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 14-1442-85
Additional Details : Weight : 0.01000kg
DescriptionApplications Tested: This eBioBV14 (BV14) antibody has been tested by western blot analysis of bEnd.3 cell lysates, and can be used in western blotting at a starting concentration of 2 µg/mL. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered. This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.
|PBS with 0.09% sodium azide; pH 7.2|
|Cadherin-5, Vascular endothelial cadherin, VE-cadherin, 7B4 antigen, CD144 antigen, CDH5|
|Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot|
For Research Use Only.