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CD150 Rat anti-Mouse, FITC, Clone: mShad150, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-1502-82

Additional Details : Weight : 0.25000kg

Product Code. 15238189

  • 1802.00 SEK / 100µg


Estimated Shipment date
from Supplier 19-08-2019
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Description

Description

CD150 (SLAM, Signaling Lymphocyte Activation Molecule) belongs to the immunoglobulin gene superfamily, and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells. Moreover, CD150 is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations CD150 gene may be associated with X-linked lympho-proliferative disease (XLP).
Specifications

Specifications

CD150
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q9QUM4
CD150, CDw150, SLAM, IPO-3, signaling lymphocytic activation molecule, SLAMF1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
mShad150
FITC
Slamf1
Liquid
Slamf1
IgG2b
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
27218
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