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CD152 (CTLA-4) Mouse anti-Human, Rhesus Monkey, eFluor® 660, Clone: 14D3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-1529-41

Additional Details : Weight : 0.23750kg

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Product Code. 15559906

  • 988.00 SEK / 25 tests


Estimated Shipment
08-01-2021
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Description

Description

A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Furthermore, due to the intracellular localization of a large portion of CTLA-4, for complete detection it may be necessary to assess intracellular expression, in addition to surface expression of CTLA-4. eFluor® 660 is a replacement for Alexa Fluor® 647. eFluor® 660 emits at 659 nm and is excited with the red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome. Excitation: 633-647 nm; Emission: 668 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function.
Specifications

Specifications

CD152 (CTLA-4)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P16410
CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human, Rhesus Monkey
Flow Cytometry
14D3
eFluor™ 660
CTLA4
Liquid
CTLA4
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
1493, 705673
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