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CD16/CD32 Rat anti-Mouse, Biotin, Clone: 93, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-0161-82
Additional Details : Weight : 0.25000kg
Description
CD16 is a 50-65 kDa cell surface molecule that exists in two forms - a transmembranous form expressed by natural killer (NK) cells, and some T cells and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC (antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD32 is expressed by B cells, monocytes, granulocytes and platelets. Further, CD32 is involved in the phagocytosis of immune complexes, the regulation of antibody production by B-cells, and variations of the CD32 gene may increase vulnerability to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms of CD32 have been found.Specifications
| CD16/CD32 | |
| Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2 | |
| P08101 | |
| FCGR3, FCGR3A, FCGR3B, CD16A, CD16B, Fc gamma Receptor III, Fc gamma Receptor 3, RP11-5K23.1, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, FCGR2, CD32, Fc gamma Receptor II, CD32 receptor 2, Fc gamma Receptor 2, FCGR2A, FCGR2B, FCGR2C, Low affinity immunoglobulin gamma Fc region receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, FCG2, Low affinity immunoglobulin gamma Fc region receptor II-c, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, FGFR2B | |
| Rat | |
| Affinity chromatography | |
| RUO | |
| Antibody | |
| Monoclonal | |
| Mouse |
| Flow Cytometry | |
| 93 | |
| Biotin | |
| Fcgr2b | |
| Liquid | |
| Fcgr2b | |
| IgG2a, lambda | |
| 100 μg | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Primary | |
| 14130 |
For Research Use Only.