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CD161 Monoclonal Antibody (10/78), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

2880.00 SEK

Specifications

Antigen CD161
Applications Flow Cytometry
Classification Monoclonal
Conjugate PerCP-eFluor 710
Form Liquid
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Products 1
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15381290
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Affymetrix eBioscience
46-1610-82
100 μg
2880.00 SEK
100µg
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Estimated Shipment: 29-04-2024
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Description

Description

Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. {ECO:0000269; PubMed:16455998, ECO:0000269; PubMed:16925668, ECO:0000269; PubMed:8077657}.

CD161 Monoclonal antibody specifically detects CD161 in Rat samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD161
Monoclonal
Liquid
RUO
IgG1 κ
Affinity chromatography
Flow Cytometry
PerCP-eFluor 710
Mouse
Rat
Primary
Antibody
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