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CD170 (Siglec F) Rat anti-Mouse, eFluor 660, Clone: 1RNM44N, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-1702-82

Additional Details : Weight : 0.09500kg

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Product Code. 15509916

  • 2538.00 SEK / 100µg


EU Stock 2
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Disclaimers:

For Research Use Only.


Description

Description

This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds glycoconjugates containing sialic acids that are commonly found on various cell types. The cytoplasmic domain of Siglec F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that initiates intracellular signaling upon ligand binding. Siglec F is expressed mostly on eosinophils and alveolar macrophages and lower levels of this receptor have also been reported on immature myelomonocytic cells. Mouse Siglec F is a functional ortholog of human Siglec 8, however, unlike human Siglec 8, mouse Siglec F is not expressed on mast cells.

This 1RNM44N antibody will recognize a formaldehyde-fixed epitope.
Specifications

Specifications

CD170 (Siglec F)
1RNM44N
eFluor™ 660
Conjugated
IgG2a
RUO
Primary
Murine
Flow Cytometry
0.2mg/mL
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
100μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal