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CD172a (SIRP alpha) Monoclonal Antibody (OX41), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-1720-82
1920.09 SEK valid until 2024-03-29
Use promo code "21615" to get your promotional price.
Additional Details : Weight : 0.09500kg
Description
Description: The monoclonal antibody OX41 reacts with rat CD172a, which is also known as signal-regulatory protein alpha (SIRPa). SIRP family members are transmembrane glycoproteins with 3 Ig-like extracellular domains and a cytoplasmic tail containing 2 immunocreceptor tyrosine-based inhibition motifs. CD172a is expressed by monocytes, macrophages, granulocytes, dendritic cells, and neurons. SIRPa association with CD47 inhibits phagocytosis of CD47 presenting cells. Studies suggest that SIRPa ligation prevents phagocytosis by inactivating paxillin and cofilin, proteins involved in cytoskeleton remodeling. Applications Reported: This OX41 antibody has been reported for use in flow cytometric analysis. Applications Tested: This OX41 antibody has been tested by flow cytometric analysis of rat lysed whole blood. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.
CD172a (SIRP alpha) Monoclonal antibody specifically detects CD172a (SIRP alpha) in Rat samples. It is validated for Flow Cytometry.Specifications
CD172a (SIRP alpha) | |
Monoclonal | |
0.2 mg/mL | |
PBS with 0.09% sodium azide; pH 7.2 | |
P97710 | |
SIRPA | |
Affinity chromatography | |
RUO | |
25528 | |
4° C, store in dark, DO NOT FREEZE! | |
Liquid |
Flow Cytometry | |
OX41 | |
APC | |
SIRPA | |
AI835480; Bit; brain Ig-like molecule with tyrosine-based activation motifs; Brain immunoglobulin like protein with tyrosine - based activation motifs; brain immunological-like with tyrosine-based motifs; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172; CD172 alpha; CD172 antigen-like family member A; CD172A; Inhibitory receptor SHPS-1; macrophage fusion receptor; Macrophage membrane protein MFP150; MFR; mSIRP-alpha1; Myd1; MYD-1; myD-1 antigen; p84; Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1); protein tyrosine phosphatase, non-receptor type substrate 1; Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1); Ptpns1; SHP substrate 1; SHP-1; SHPS1; SHPS-1; signal regulatory protein alpha; signal-regulatory protein alpha; signal-regulatory protein alpha-1; Signal-regulatory protein alpha-2; Signal-regulatory protein alpha-3; SIRP; Sirpa; SIRPalpha; Sirp-alpha-1; SIRPalpha2; Sirp-alpha-2; Sirp-alpha-3; | |
Mouse | |
100 μg | |
Primary | |
Rat | |
Antibody | |
IgG2a κ |
For Research Use Only.