CD180 (RP105) Mouse anti-Human, Clone: MHR73-11, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-1809-82
Additional Details : Weight : 0.01000kg
DescriptionApplications Tested: The MHR73-11 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, RP105/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). RP105/MD1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria.
|PBS with 0.09% sodium azide; pH 7.2|
|LY64, Ly78, MGC126233, MGC126234, RP105|
|Flow Cytometry, Functional Assay, Immunohistochemistry, Immunoprecipitation|
For Research Use Only.