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CD184 (CXCR4) Monoclonal Antibody (2B11), PE-eFluor™ 610, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
1130.00 SEK - 3370.00 SEK
Specifications
Antigen | CD184 (CXCR4) |
---|---|
Clone | 2B11 |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15590587
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Affymetrix eBioscience
61-9991-82 |
100 μg |
3370.00 SEK
100µg |
In Stock Log in to see stock. |
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15580587
|
Affymetrix eBioscience
61-9991-80 |
25 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The 2B11 monoclonal antibody reacts with mouse and human CXCR4, also known as CD184, Fusin, LESTR, or HUMSTR. Fusin is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains, and functions as a coreceptor for X4 HIV-1 entry into CD4+ cells. In addition it has been shown to play a role in lymphocyte migration. The ligand for CXCR4 is SDF1. CXCR4 is required for maintece of granulocyte progenitors in the bone marrow and essential for B cell development. Expression of CXCR4 is different between mice and human. In the thymus CXCR4 is restricted to CD4+CD8+ cells while in the spleen predomit expression is found on B lymphocytes. The monoclonal antibody 2B11 recognizes the amino terminus of CXCR4 and has been reported to have functional activity; it does not block SDF1a but causes internalization of the receptor. Applications Reported: This 2B11 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 2B11 antibody has been tested by flow cytometric analysis of mouse thymocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
CD184 (CXCR4) Monoclonal antibody specifically detects CD184 (CXCR4) in Mouse samples. It is validated for Flow Cytometry.Specifications
CD184 (CXCR4) | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
P70658 | |
Cxcr4 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Cxcr4 |
2B11 | |
Flow Cytometry | |
PE-eFluor 610 | |
Rat | |
Mouse | |
12767 | |
IgG2b κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.