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CD185 (CXCR5) Monoclonal Antibody (MU5UBEE), eFluor™ 450, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1334.00 SEK - 3910.00 SEK

Specifications

Antigen CD185 (CXCR5)
Clone MU5UBEE
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15589826
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Affymetrix eBioscience
48-9185-42
100 Tests
3910.00 SEK
100 tests
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15579826
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Affymetrix eBioscience
48-9185-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: The MU5UBEE monoclonal antibody reacts with human and non-human primate CD185. CD185, which is also known as C-X-C chemokine receptor 5 (CXCR5) and Burkitt lymphoma receptor 1 (BLR1), is a seven transmembrane G protein-coupled receptor originally identified in Burkitt's lymphoma. In peripheral blood, CD185 is expressed on B cells, CD4+ T cells (but not Th1 or Th2 cells), as well as on a subpopulation of memory (CD45RO+) T cells. Circulating CD185+ T cells are in a resting state and migrate to the lymph nodes due to expression of CCR7 and CD62L. In tonsil, CD185 is expressed on nearly all CD4+ cells together with CD45RO and activation markers such as CD69 and ICOS. Tonsillar CD185+ cells have been shown to induce antibody production when co-cultured with B cells, thus supporting their role in providing help to B cells. Furthermore, this chemokine receptor plays a critical role in lymphocyte trafficking, in particular T cell migration into the B cell follicles of germinal centers in response to CXCL13, making CD185 an established marker of follicular helper T cells. The MU5UBEE monoclonal antibody also crossreacts with Rhesus macaque. Applications Reported: This MU5UBEE antibody has been reported for use in flow cytometric analysis. Applications Tested: This MU5UBEE antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.06 μg) per test.

CD185 (CXCR5) Monoclonal antibody specifically detects CD185 (CXCR5) in Human, Non-human Primate, Rhesus Monkey samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD185 (CXCR5)
5 μL/Test
Monoclonal
Liquid
RUO
P32302
CXCR5
Primary
4° C, store in dark, DO NOT FREEZE!
CXCR5
MU5UBEE
Flow Cytometry
eFluor 450
Mouse
Human, Non-human Primate, Rhesus Monkey
643, 701792
IgG2b κ
Affinity chromatography
Antibody
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