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CD185 (CXCR5) Monoclonal Antibody (MU5UBEE), eFluor™ 450, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
1334.00 SEK - 3910.00 SEK
Specifications
Antigen | CD185 (CXCR5) |
---|---|
Clone | MU5UBEE |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15589826
|
Affymetrix eBioscience
48-9185-42 |
100 Tests |
3910.00 SEK
100 tests |
Estimated Shipment: 07-05-2024 Log in to see stock. |
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15579826
|
Affymetrix eBioscience
48-9185-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The MU5UBEE monoclonal antibody reacts with human and non-human primate CD185. CD185, which is also known as C-X-C chemokine receptor 5 (CXCR5) and Burkitt lymphoma receptor 1 (BLR1), is a seven transmembrane G protein-coupled receptor originally identified in Burkitt's lymphoma. In peripheral blood, CD185 is expressed on B cells, CD4+ T cells (but not Th1 or Th2 cells), as well as on a subpopulation of memory (CD45RO+) T cells. Circulating CD185+ T cells are in a resting state and migrate to the lymph nodes due to expression of CCR7 and CD62L. In tonsil, CD185 is expressed on nearly all CD4+ cells together with CD45RO and activation markers such as CD69 and ICOS. Tonsillar CD185+ cells have been shown to induce antibody production when co-cultured with B cells, thus supporting their role in providing help to B cells. Furthermore, this chemokine receptor plays a critical role in lymphocyte trafficking, in particular T cell migration into the B cell follicles of germinal centers in response to CXCL13, making CD185 an established marker of follicular helper T cells. The MU5UBEE monoclonal antibody also crossreacts with Rhesus macaque. Applications Reported: This MU5UBEE antibody has been reported for use in flow cytometric analysis. Applications Tested: This MU5UBEE antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (0.06 μg) per test.
CD185 (CXCR5) Monoclonal antibody specifically detects CD185 (CXCR5) in Human, Non-human Primate, Rhesus Monkey samples. It is validated for Flow Cytometry.Specifications
CD185 (CXCR5) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
P32302 | |
CXCR5 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
CXCR5 |
MU5UBEE | |
Flow Cytometry | |
eFluor 450 | |
Mouse | |
Human, Non-human Primate, Rhesus Monkey | |
643, 701792 | |
IgG2b κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.