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CD19 Rat anti-Mouse, FITC, Clone: eBio1D3 (1D3), eBioscience™

Rat Monoclonal Antibody

766.00 SEK - 4170.00 SEK

Specifications

Antigen CD19
Clone eBio1D3 (1D3)
Target Species Mouse
Conjugate FITC
Isotype IgG2a, kappa
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Products 4
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15288039
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Affymetrix eBioscience
11-0193-81
50 μg
766.00 SEK
50µg
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In stock, ready to ship: 2
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15219185
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Affymetrix eBioscience
11-0193-82
100 μg
1362.00 SEK
100µg
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In stock, ready to ship: 4
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15298039
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Affymetrix eBioscience
11-0193-85
500 μg
2465.00 SEK
500µg
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Estimated Shipment
14-12-2020
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15208049
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Affymetrix eBioscience
11-0193-86
1 mg
4170.00 SEK
1mg
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Estimated Shipment
14-12-2020
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Description

Description

CD19 is a member of the immunoglobulin superfamily and has two Ig like domains. The CD19 molecule is expressed on 100% of the peripheral B cells as defined by expression of kappa or lambda light chains. CD19 appears to be expressed on myeloid leukemia cells, particularly those of monocytic lineage. Leukemia phenotype studies have demonstrated that the earliest and broadest B cell restricted antigen is the CD19 antigen. The receptor for CD19 is an important functional regulator of normal and maligt B cell proliferation, and is expressed in all B cell precursor leukemias. Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. CD19 is a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Besides being a signal-amplifying coreceptor for the B cell receptor (BCR), CD19 can also signal independently of BCR co-ligation and is a central regulatory component upon which multiple signaling pathways converge. Mutation of the CD19 gene results in hypogammaglobulinemia, whereas CD19 overexpression causes B cell hyperactivity.
Specifications

Specifications

CD19
Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
eBio1D3 (1D3)
FITC
Flow Cytometry
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.