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CD193 (CCR3) Monoclonal Antibody (eBio5E8-G9-B4 (5E8-G9-B4)), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1326.00 SEK - 3345.00 SEK

Specifications

Antigen CD193 (CCR3)
Clone eBio5E8-G9-B4 (5E8-G9-B4)
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
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Product Code Brand Quantity Price Quantity & Availability  
15518046
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Affymetrix eBioscience
17-1939-42
100 Tests
3345.00 SEK
100 tests
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15508046
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Affymetrix eBioscience
17-1939-41
25 Tests This item is currently unavailable or has been discontinued.
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Description

Description

Description: The eBio5E8-G9-B4 monoclonal antibody reacts with human CD193 (CCR3, CKR3). CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4. CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function. In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells. CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma. CD193 can also serve as a receptor for HIV-1 cell entry. Applications Reported: This eBio5E8-G9-B4 (5E8-G9-B4) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBio5E8-G9-B4 (5E8-G9-B4) antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood. This can be used at 5 μL (0.25 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

CD193 (CCR3) Monoclonal antibody specifically detects CD193 (CCR3) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD193 (CCR3)
5 μL/Test
Monoclonal
Liquid
RUO
P51677
CCR3
Primary
4° C, store in dark, DO NOT FREEZE!
CCR3
eBio5E8-G9-B4 (5E8-G9-B4)
Flow Cytometry
APC
Mouse
Human
1232
IgG2b κ
Affinity chromatography
Antibody
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