CD197 (CCR7), Biotin, clone: 3D12, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 13-1979-82
Additional Details : Weight : 0.25000kg
DescriptionIt is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. It is recommended that the staining incubation time be increased to at least 45 minutes at 2-8°C for optimal staining. Filtration: 0.2 μm post-manufacturing filtered. CCR7 is a member of the G protein coupled receptor family, which is a subfamily of chemokines. CCR7 was identified to be induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. CCR7 is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries. Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|Bukitt′s lymphoma receptor 2; C-C chemokine receptor type 7; CC chemokine receptor 7; CCR-7; CD197; Chemokine (C-C Motif) Receptor 7; chemokine (C-C) receptor 7; CMKBR7; EBI1; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 Beta Receptor|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.