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CD197 (CCR7) Rat anti-Human, FITC, Clone: 3D12, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-1979-41

Additional Details : Weight : 0.23750kg

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Product Code. 15506516

  • 864.00 SEK / 25 tests


Estimated Shipment date
from Supplier 05-07-2019
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Description

Description

It is recommended that the staining incubation time be increased to at least 45 minutes at 2-8°C for optimal staining. Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser. Filtration: 0.2 μm post-manufacturing filtered. CCR7 is a member of the G protein coupled receptor family, which is a subfamily of chemokines. CCR7 was identified to be induced by the Epstein Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. CCR7 is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries. Receptors for the C - C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
Specifications

Specifications

CD197 (CCR7)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P32248
Bukitt′s lymphoma receptor 2; C-C chemokine receptor type 7; CC chemokine receptor 7; CCR-7; CD197; Chemokine (C-C Motif) Receptor 7; chemokine (C-C) receptor 7; CMKBR7; EBI1; EBV-induced G protein-coupled receptor 1; EBV-induced G-protein coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1; lymphocyte-specific G protein-coupled peptide receptor; MIP-3 Beta Receptor
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
3D12
FITC
CCR7
Liquid
CCR7
IgG2a, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
1236
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