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CD20, PE, clone: AISB12, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-0201-80

Additional Details : Weight : 0.25000kg

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Product Code. 15248479

  • 1290.00 SEK / 25µg


Estimated Shipment date
from Supplier 30-10-2018
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Description

Description

Description: The AISB12 monoclonal antibody reacts with mouse CD20. CD20 is a B cell-specific 32kDa membrane protein involved in intracellular calcium regulation. CD20 expression begins after the induction of CD19 during development, and is coexpressed with IgM during the pre-B to immature B cell transition in bone marrow. Expression then increases during maturation with almost all mature cells expressing some level of CD20. The human CD20 antigen has proven to be an effective immunotherapeutic target in B cell lymphoma and several autoimmune diseases including rheumatoid arthritis and type I diabetes. CD20 consists of 4 transmembrane domains and a 44 amino acid extracellular loop domain where AISB12 binds.Applications Reported: This AISB12 antibody has been reported for use in flow cytometric analysis.Applications Tested: This AISB12 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD20
Monoclonal
0.2mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P19437
B1, Bp35, CD20, LEU-16, MGC3969, MS4A1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
AISB12
PE
Ms4a1
Liquid
Ms4a1
IgG2a
25μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
12482
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