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CD200 Rat anti-Mouse, Clone: OX90, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5200-80

Additional Details : Weight : 0.01000kg

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Product Code. 15207407

  • 534.00 SEK / 25µg


Estimated Shipment date
from Supplier 03-04-2020
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Description

Description

2 μm post-manufacturing filtered. CD200 is a type-1 membrane glycoprotein that contains two immunoglobulin domains, and belongs to the immunoglobulin superfamily. CD200 is a broadly distributed cell surface glycoprotein that interacts with a receptor on myeloid cells (CD200R) and is implicated in locally preventing macrophage activation. Distant, but recognizable, homologues of CD200 have been identified in many herpesviruses and poxviruses. Studies of the related genes in mouse and rat suggest that CD200 may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms of CD200 have been found. Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
Specifications

Specifications

CD200
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
O54901
MOX1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
OX90
Unconjugated
Cd200
Liquid
Cd200
IgG2a, kappa
25 μg
4° C
Primary
17470
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