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CD201 (EPCR) Monoclonal Antibody (eBio1560 (1560)), Biotin, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

3110.00 SEK

Specifications

Antigen CD201 (EPCR)
Clone eBio1560 (1560)
Concentration 0.5 mg/mL
Applications Flow Cytometry, Immunohistochemistry
Classification Monoclonal
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Products 1
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15249769
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Affymetrix eBioscience
13-2012-82
100 μg
3110.00 SEK
100µg
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Estimated Shipment: 10-04-2024
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Description

Description

Description: The eBio1560 monoclonal antibody reacts with mouse Endothelial Protein C Receptor (EPCR, CD201), a 25 kDa Type 1 transmembrane protein expressed on endothelial cells. EPCR exhibits sequence and structural homology with the MHC class I/CD1 family of proteins. EPCR is a ligand for Protein C and plays an important role in augmenting Protein C activation by the thrombin-thrombomodulin complex and in regulating blood coagulation and inflammation. Deletion of EPCR results in embryonic lethality, at least partically due to placental thrombosis. Recently, it was demonstrated that EPCR expression identified cells in the bone marrow that are capable of hematopoietic reconstitution activity comparable to hematopoietic stem cells isolated with conventional methods. The eBio1560 monoclonal antibody can be used for the detection of these hematopoietic stem cells, however the eBiomRCR-16 monoclonal antibody should only be used for the detection of CD201 on endothelial cells. Applications Reported: This eBio1560 (1560) antibody has been reported for use in flow cytometric analysis, and immunohistochemical staining. Applications Tested: This eBio1560 (1560) antibody has been tested by flow cytometric analysis of bEnd.3 cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL.

The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy.
Specifications

Specifications

CD201 (EPCR)
0.5 mg/mL
Monoclonal
Liquid
RUO
Q64695
Procr
Primary
4° C, store in dark, DO NOT FREEZE!
Procr
eBio1560 (1560)
Flow Cytometry, Immunohistochemistry
Biotin
Rat
Mouse
19124
IgG2b κ
Affinity chromatography
Antibody
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