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Beskrivning
This antibody recognizes the intracellular carboxy-terminal part of CD206 and MRC1L1.
CD206 (macrophage mannose receptor, MMR), also known as mannose receptor C1 (MRC1), is a type I transmembrane glycoprotein serving as pattern recognition receptor for carbohydrate groups on the surface of bacteria, fungi and other pathogens. Expressed mainly on tissue macrophages and dendritic cells, CD206 mediates endocytosis of these pathogens and presentation of their antigens to the adaptive immune system. CD206 can also be detected in a soluble form in human plasma and is elevated in patients with acute sepsis.
Specifikationer
Specifikationer
| Antigen | CD206 |
| Användningsområden | Flow Cytometry, Immunoprecipitation, Western Blot |
| Klassificering | Monoclonal |
| Klona | 2A6A10 |
| Koncentration | 1 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 |
| Gen | MRC1 |
| Genaccessionsnr. | P22897, Q61830 |
| Gene Alias | CD206, CLEC13D, Macrophage mannose receptor 1, Mannose receptor, mannose receptor, C type 1, MMR, MRC1 |
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Produkttitel
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