missing translation for 'onlineSavingsMsg'
Learn More

CD22 Mouse anti-Human, PE-Cyanine7, Clone: eBio4KB128 (4KB128), eBioscience™ Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen 25-0229-42

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 16616314

  • 4065.00 SEK / 100 units
Estimated Shipment: 23-08-2022
to see stock.

Please to purchase this item. Need a web account? Register with us today!


Description

Description

The eBio4KB128 MAb recognizes human CD22 (Siglec-2), which is a member of the siglec subgroup of the Ig superfamily. CD22 is a type I transmembrane glycoprotein composed of two polypeptide chains, CD22alpha and CD22beta, of 130 and 140 kDa respectively, produced by alternative splicing of the CD22 gene. CD22 is expressed at high levels on mature B cells and B cell lymphomas. The extracellular portion of CD22 contains seven Ig-like domains, some of which are capable of binding ligands with sialic acid moieties expressed on epithelial, endothelial, B and T cells. The intracellular portion of CD22 contains 6 tyrosine residues contained within immunotyrosine-based inhibitory motifs (ITIM) and immunotyrosine-based activation-like motifs, which are phosphorylated upon B-cell receptor engagement, which enables CD22 to participate in the positive and negative regulation of B-cell receptor signaling.

CD22 Monoclonal antibody specifically detects CD22 in Human samples. It is validated for Flow Cytometry
Specifications

Specifications

CD22
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P20273
Mouse
100 Tests
Primary
Human
Antibody
IgG1 κ
Flow Cytometry
eBio4KB128 (4KB128)
PE-Cyanine7
CD22
A530093D23; B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; Cd22; CD22 antigen; CD22 molecule; FLJ22814; Leu-14; Lyb8; Lyb-8; MGC130020; sialic acid binding Ig-like lectin 2; sialic acid-binding Ig-like lectin 2; Siglec2; SIGLEC-2; T-cell surface antigen Leu-14
Affinity chromatography
RUO
933
4° C, store in dark, DO NOT FREEZE!
Liquid
Videos
SDS
Documents
Certificates
Special Offers

Special Offers