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CD223 (LAG-3) Monoclonal Antibody (3DS223H), APC-eFluor™ 780, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

4090.00 SEK

Specifications

Clone 3DS223H
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
Conjugate APC-eFluor 780
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Products 1
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15569576
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Affymetrix eBioscience
47-2239-42
100 Tests
4090.00 SEK
100 tests
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Description

Description

Description: This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70-kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells). This 3DS223H antibody will recognize a formaldehyde-fixed epitope. Applications Reported: This 3DS223H antibody has been reported for use in flow cytometric analysis. Applications Tested: This 3DS223H antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5 μL (0.125 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. APC-eFluor™ 780 emits at 780 nm and is excited with the Red laser (633 nm). Please make sure that your instrument is capable of detecting this fluorochome.

CD223 (LAG-3) Monoclonal antibody specifically detects CD223 (LAG-3) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

3DS223H
Flow Cytometry
APC-eFluor 780
Mouse
Human
3902
IgG1 κ
Affinity chromatography
Antibody
5 μL/Test
Monoclonal
Liquid
RUO
P18627
LAG3
Primary
4° C, store in dark, DO NOT FREEZE!
LAG3
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Documents

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