CD25, Biotin, clone: OX39, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 13-0390-85
Additional Details : Weight : 0.25000kg
DescriptionDescription: The OX39 monoclonal antibody reacts with mouse CD25, the 55kDa interleukin-2 receptor alpha (IL-2R alpha). CD25 is expressed by early progenitors of the T and B lineages as well as by activated mature T and B lymphocytes. By itself, CD25 binds IL-2 only with low affinity. However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor. CD25 plays a role in lymphocyte differentiation and activation/proliferation.The OX39 clone has been shown to deplete CD25 cells in vivo.Applications Reported: This OX39 antibody has been reported for use in flow cytometric analysis and immunohistochemistry.Applications Tested: This OX39 antibody has been tested by flow cytometric analysis of rat splenocytes. This can be used at less than or equal to 0.125 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|IL2 RA antibody, Il2ra antibody, Interleukin 2 receptor alpha chain antibody, TAC antigen antibody, IL-2R alpha chain|
|Flow CytometryþImmunohistochemistry (Frozen)|
|Store at 2-8°C. Do not freeze.|
For Research Use Only.