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CD252 (OX40 Ligand) Rat anti-Mouse, PE, Clone: RM134L, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-5905-83

Additional Details : Weight : 0.25000kg

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Product Code. 15228909

  • 2505.00 SEK / 200µg


Estimated Shipment date
from Supplier 03-06-2019
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Description

Description

The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predomitly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
Specifications

Specifications

CD252 (OX40 Ligand)
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P43488
Ath-1, Ath1, TXGP1, Txgp1l, gp34, TNFSF4, CD252, OX40 Ligand
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
RM134L
PE
Tnfsf4
Liquid
Tnfsf4
IgG2b, kappa
200 μg
4° C, store in dark, DO NOT FREEZE!
Primary
22164
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