missing translation for 'onlineSavingsMsg'
Learn More

CD258 (LIGHT) Mouse anti-Human, PE, Clone: 7-3 (7), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-2589-42

Additional Details : Weight : 0.23750kg

 View more versions of this product

Product Code. 15516956

  • 2489.00 SEK / 100 tests


Estimated Shipment date
from Supplier 02-01-2018
Add to basket

Disclaimers:

For Research Use Only.


Description

Description

This 7-3 (7) monoclonal antibody reacts with human CD258 (also known as LIGHT), a 29kDa type II transmembrane protein that is a member of the TNF ligand superfamily related to lymphotoxin-ß (LT-ß). Expressed on activated T cells, particularly CD8+ T cells, LIGHT plays a role in cell survival, inflammation, and tumor eradication. Furthermore, upon binding its ligand, herpesvirus entry mediator (HVEM), LIGHT induces a costimulatory effect on T cells, enhancing T cell proliferation and cytokine production. LIGHT has also been shown to indirectly interact with the LT-ß receptor.
Specifications

Specifications

CD258 (LIGHT)
7-3 (7)
PE
Conjugated
IgG1
RUO
Primary
Human
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Videos