CD261 (DR4) Mouse anti-Human, Clone: DJR1, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 14-6644-80
Additional Details : Weight : 0.01000kg
DescriptionTRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
|PBS with 0.09% sodium azide; pH 7.2|
|APO2, CD261, DR4, MGC9365, TRAILR-1, TRAILR1|
|Flow Cytometry, Immunohistochemistry (Frozen)|
For Research Use Only.