missing translation for 'onlineSavingsMsg'
Learn More

CD261 (DR4) Monoclonal Antibody (DJR1), PE, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1464.00 SEK - 3105.00 SEK

Specifications

Antigen CD261 (DR4)
Clone DJR1
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15507076
View Documents Promotion Details
Affymetrix eBioscience
12-6644-41
25 Tests
1464.00 SEK
25 tests
View alternative products
Save Up to 
»
Estimated Shipment: 19-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
15517076
View Documents Promotion Details
Affymetrix eBioscience
12-6644-42
100 Tests
3105.00 SEK
100 tests
View alternative products
Save Up to 
»
Estimated Shipment: 09-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The DJR1 monoclonal antibody reacts with human DR4, also known as TRAIL-R1. DR4 binds to TRAIL, activates NF-kappaB, and induces TRAIL-mediated apoptosis. DR4 is expressed by a variety of human tumor cells and at very low level on human leukocytes. Expression has also been found inside the cell on some cell lines (Zhang et al). This has been confirmed with intracellular staining of Jurkat cell line. Please contact tech@ebioscience.com for more information. Applications Reported: The DJR1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This DJR1 antibody has been pre-titrated and tested by flow cytometric analysis of human DR4-transfected cells. This can be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered.

TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
Specifications

Specifications

CD261 (DR4)
5 μL/Test
Monoclonal
Liquid
RUO
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; sCD261; soluble CD261; soluble TRAIL; sTRAIL; TNF receptor superfamily member 10a; TNF-related apoptosis-inducing ligand receptor 1; TNFRSF10A; TRAIL R1; TRAIL receptor 1; TRAILR1; TRAIL-R1; TRAILR-1; tumor necrosis factor receptor superfamily member 10A; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a
TNFRSF10A
Primary
4° C, store in dark, DO NOT FREEZE!
TNFRSF10A
DJR1
Flow Cytometry
PE
Mouse
Human
O00220
8797
IgG1 κ
Affinity chromatography
Antibody
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only.