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Invitrogen™ CD267 (TACI) Monoclonal Antibody (166010)

Beskrivning
Reconstitute at 0.5 mg/mL in sterile PBS.
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
Specifikationer
Specifikationer
| Antigen | CD267 (TACI) |
| Användningsområden | ELISA, Flow Cytometry, Western Blot |
| Klassificering | Monoclonal |
| Klona | 166010 |
| Koncentration | 0.5 mg/mL |
| Konjugera | Unconjugated |
| Formulering | PBS with trehalose and no preservative |
| Gen | TNFRSF13B |
| Genaccessionsnr. | Q9ET35 |
| Gene Alias | 1200009E08Rik; CD267; CVID; CVID2; IGAD2; NEWGENE_1595998; RYZN; TACI; TNF receptor superfamily member 13B; Tnfrsf13b; TNFRSF14B; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B |
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Produkttitel
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