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CD267 (TACI) Mouse anti-Human, PE, Clone: 11H3, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 12-9217-41

Additional Details : Weight : 0.23750kg

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Product Code. 15517196

  • 1240.00 SEK / 25 tests


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

The 11H3 antibody reacts with human TACI, also known as tumor necrosis factor receptor 13B. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. TACI mRNA and protein are found predominantly in B-cells and correlate with BLyS binding in a panel of B-cell lines. TACI interacts with nanomolar affinity with the BLyS-related tumor necrosis factor homologue APRIL for which no clear in vivo role has been described. 11H3 does not block binding of BAFF/BLyS to TACI.
Specifications

Specifications

CD267 (TACI)
11H3
PE
Conjugated
Murine
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
TNFRSF13B
IgG2a
RUO
Primary
Human