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CD273 (B7-DC) Monoclonal Antibody (MIH18), Alexa Fluor™ 488, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

1782.00 SEK - 4160.00 SEK

Specifications

Antigen CD273 (B7-DC)
Clone MIH18
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16587100
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Affymetrix eBioscience
53-5888-41
25 Tests
1782.00 SEK
Pack of 25
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Estimated Shipment: 22-04-2024
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16597100
View Documents Promotion Details
Affymetrix eBioscience
53-5888-42
100 Tests
4160.00 SEK
Pack of 100
View alternative products
Save Up to 
»
Estimated Shipment: 22-04-2024
to see stock.
Please to purchase this item. Need a web account? Register with us today!
Description

Description

Description: The MIH18 monoclonal antibody reacts with human CD273, also known as PD-L2 or B7-DC, a member of the B7 family that has a predicted molecular weight of approximately 25 kDa, and belongs to the Ig superfamily. B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. MIH18 is a useful tool for studies to elucidate the exact function of B7-DC/PD-L2 in APC/T cell interaction, and to characterize the expression pattern of this molecule in humans. MIH18 is a blocking antibody. Applications Reported: This MIH18 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MIH18 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser

CD273 (B7-DC) Monoclonal antibody specifically detects CD273 (B7-DC) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD273 (B7-DC)
5 μL/Test
Monoclonal
Liquid
RUO
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; butyrophilin-like protein; CD273; F730015O22Rik; MGC124039; MGC124040; PD1 ligand 2; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; Pdl2; PD-L2; Programmed cell death 1 ligand 2; programmed death ligand 2
PDCD1LG2
Primary
4° C, store in dark, DO NOT FREEZE!
PDCD1LG2
MIH18
Flow Cytometry
Alexa Fluor 488
Mouse
Human
Q9BQ51
80380
IgG1 κ
Affinity chromatography
Antibody
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