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CD273 (B7-DC) Monoclonal Antibody (MIH18), Alexa Fluor™ 488, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
1782.00 SEK - 4160.00 SEK
Specifications
Antigen | CD273 (B7-DC) |
---|---|
Clone | MIH18 |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16587100
|
Affymetrix eBioscience
53-5888-41 |
25 Tests |
1782.00 SEK
Pack of 25 |
Estimated Shipment: 22-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
16597100
|
Affymetrix eBioscience
53-5888-42 |
100 Tests |
4160.00 SEK
Pack of 100 |
Estimated Shipment: 22-04-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Description: The MIH18 monoclonal antibody reacts with human CD273, also known as PD-L2 or B7-DC, a member of the B7 family that has a predicted molecular weight of approximately 25 kDa, and belongs to the Ig superfamily. B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. MIH18 is a useful tool for studies to elucidate the exact function of B7-DC/PD-L2 in APC/T cell interaction, and to characterize the expression pattern of this molecule in humans. MIH18 is a blocking antibody. Applications Reported: This MIH18 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MIH18 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser
CD273 (B7-DC) Monoclonal antibody specifically detects CD273 (B7-DC) in Human samples. It is validated for Flow Cytometry.Specifications
CD273 (B7-DC) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; butyrophilin-like protein; CD273; F730015O22Rik; MGC124039; MGC124040; PD1 ligand 2; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; Pdl2; PD-L2; Programmed cell death 1 ligand 2; programmed death ligand 2 | |
PDCD1LG2 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
PDCD1LG2 |
MIH18 | |
Flow Cytometry | |
Alexa Fluor 488 | |
Mouse | |
Human | |
Q9BQ51 | |
80380 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |