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CD273 (B7-DC) Mouse anti-Human, Alexa Fluor 488, Clone: MIH18, eBioscience™ Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-5888-42

Additional Details : Weight : 0.01000kg

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Product Code. 16597100

  • 3745.00 SEK / Pack of 100
Estimated Shipment: 02-09-2022
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Description

Description

The MIH18 monoclonal antibody reacts with human CD273, also known as PD-L2 or B7-DC, a member of the B7 family that has a predicted molecular weight of approximately 25 kDa, and belongs to the Ig superfamily. B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. MIH18 is a useful tool for studies to elucidate the exact function of B7-DC/PD-L2 in APC/T cell interaction, and to characterize the expression pattern of this molecule in humans. MIH18 is a blocking antibody. Applications Reported: This MIH18 antibody has been reported for use in flow cytometric analysis. Applications Tested: This MIH18 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.5 μg) per test. A test is defined as the amount ( μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser

CD273 (B7-DC) Monoclonal antibody specifically detects CD273 (B7-DC) in Human samples. It is validated for Flow Cytometry
Specifications

Specifications

CD273 (B7-DC)
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Q9BQ51
Mouse
100 Tests
Primary
Human
Antibody
IgG1 κ
Flow Cytometry
MIH18
Alexa Fluor 488
PDCD1LG2
B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; butyrophilin-like protein; CD273; F730015O22Rik; MGC124039; MGC124040; PD1 ligand 2; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; PDCD1LG2; Pdl2; PD-L2; Programmed cell death 1 ligand 2; programmed death ligand 2
Affinity chromatography
RUO
80380
4° C, store in dark, DO NOT FREEZE!
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