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CD273 (B7-DC), FITC, clone: 122, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-9972-85

Additional Details : Weight : 0.25000kg

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Product Code. 15268399

  • 3530.00 SEK / 500µg


Estimated Shipment date
from Supplier 26-06-2018
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Description

Description

Description: The 122 monoclonal antibody reacts with mouse B7-DC, also known as PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of approximately 25kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages in the mouse. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. 122 has been demonstrated to block binding of TY25 (Cat. No.14-5986), another mAb specific for mouse B7-DC.Applications Reported: This 122 antibody has been reported for use in flow cytometric analysis.Applications Tested: This 122 antibody has been tested by flow cytometric analysis of mouse bone marrow derived dendritic cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD273 (B7-DC)
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q9WUL5
B7-DC, Btdc, F730015O22Rik, MGC124039, MGC124040, PD-L2
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
122
FITC
Pdcd1lg2
Conjugated
Pdcd1lg2
IgG2a, kappa
500μg
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
58205
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