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CD273 (B7-DC) Monoclonal Antibody (122), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

1384.00 SEK - 3440.00 SEK

Specifications

Antigen CD273 (B7-DC)
Clone 122
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15569476
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Affymetrix eBioscience
46-9972-80
25 μg
1384.00 SEK
25µg
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Estimated Shipment: 09-04-2024
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15579476
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Affymetrix eBioscience
46-9972-82
100 μg
3440.00 SEK
100µg
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Description

Description

Description: The 122 monoclonal antibody reacts with mouse B7-DC, also known as PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of approximately 25 kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by subpopulations of dendritic cells and monocytes/macrophages in the mouse. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, rather it is a ligand for PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. 122 has been demonstrated to block binding of TY25 (Cat. No. 14-5986), another mAb specific for mouse B7-DC. Applications Reported: This 122 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 122 antibody has been tested by flow cytometric analysis of mouse bone marrow derived dendritic cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

CD273 (B7-DC) Monoclonal antibody specifically detects CD273 (B7-DC) in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD273 (B7-DC)
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
B7 dendritic cell molecule; B7DC; B7-DC; bA574F11.2; Btdc; Butyrophilin B7-DC; butyrophilin-like protein; CD273; F730015O22Rik; MGC124039; MGC124040; PD1 ligand 2; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; PDCD1L2; Pdcd1lg2; Pdl2; PD-L2; Programmed cell death 1 ligand 2; programmed death ligand 2
PDCD1LG2
Primary
4° C, store in dark, DO NOT FREEZE!
PDCD1LG2
122
Flow Cytometry
PerCP-eFluor 710
Rat
Mouse
Q9WUL5
58205
IgG2a κ
Affinity chromatography
Antibody
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