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CD274 (PD-L1, B7-H1) Mouse anti-Human, Clone: MIH1, eBioscience™

Mouse Monoclonal Antibody

502.00 SEK - 978.00 SEK

Specifications

Antigen CD274 (PD-L1, B7-H1)
Clone MIH1
Target Species Human
Conjugate Unconjugated
Isotype IgG1, kappa
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15207667 Affymetrix eBioscience
14-5983-82
100 μg 978.00 SEK
100µg View alternative products
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EU Stock 6
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15297657 Affymetrix eBioscience
14-5983-80
25 μg 502.00 SEK
25µg View alternative products
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EU Stock 4
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Description

Description

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a recently described B7 family member. To date, one specific receptor has been identified that can be ligated by PD-L1. This receptor, programmed death receptor 1 (PD-1), has been shown to negatively regulate T-cell receptor (TCR) signaling. Upon ligating its receptor, PD-L1 has been reported to decrease TCR-mediated proliferation and cytokine production. PD-L1 expression was found to be abundant on many murine and human cancers and could be further up-regulated upon IFN-gamma stimulation. Thus, PD-L1 might play an important role in tumor immune evasion.
Specifications

Specifications

CD274 (PD-L1, B7-H1)
Human
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C
MIH1
Unconjugated
Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.