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CD279 (PD-1) Armenian Hamster anti-Mouse, Functional Grade, Clone: J43, eBioscience™

Armenian Hamster Monoclonal Antibody

1016.00 SEK - 3065.00 SEK

Specifications

Antigen CD279 (PD-1)
Clone J43
Target Species Mouse
Conjugate Functional Grade
Isotype IgG
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Products 3
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
15208857
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Affymetrix eBioscience
16-9985-81
50 μg
1016.00 SEK
50µg
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Estimated Shipment
24-02-2021
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15218857
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Affymetrix eBioscience
16-9985-82
100 μg
1564.00 SEK
100µg
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Estimated Shipment
24-02-2021
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15228857
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Affymetrix eBioscience
16-9985-85
500 μg
3065.00 SEK
500µg
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Estimated Shipment
24-02-2021
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Description

Description

A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Endotoxin: Less than 0.001 ng/ug antibody as determined by the LAL assay. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of ""danger signals"" such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases. Despite its predicted molecular weight, PD-1 often migrates at higher molecular weight in SDS-PAGE.
Specifications

Specifications

CD279 (PD-1)
Mouse
IgG
Monoclonal
Liquid
Antibody
4° C
J43
Functional Grade
Flow Cytometry, Functional Assay
Primary
Monoclonal
PBS with no preservative; pH 7.2
RUO
SDS

For Research Use Only.