missing translation for 'onlineSavingsMsg'
Learn More

CD279 (PD-1), clone: RMP1-14, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-9982-81

Additional Details : Weight : 0.01000kg

 View more versions of this product

Product Code. 15258307

  • 926.00 SEK / 50µg


EU Stock 1
Add to basket

Description

Description

Description: This antibody reacts with mouse PD-1 (programmed death-1), a 55kDa member of the Ig superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease in mice. PD-1 is expressed mainly on activated T and B lymphocytes. Two novel B7 Family members have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Similar to J43, another mAb to mouse PD-1 (cat. 16-9985), RMP1-14 blocks the binding of both B7-H1-Ig and B7-DC-Ig to PD-1 transfectants.Applications Reported: The RMP1-14 antibody has been reported for use in flow cytometric analysis. (Please use Functional Grade purified RMP1-14, cat. 16-9982, in functional assays.).Applications Tested: The RMP1-14 antibody has been tested by flow cytometric analysis of 3 day Con A activated splenocytes. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD279 (PD-1)
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
Q02242
PD1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry, Functional Assay
RMP1-14
Unconjugated
Pdcd1
Liquid
Pdcd1
IgG2a, kappa, kappa
50μg
4° C
Primary
18566
Videos

For Research Use Only.