CD282 (TLR2), FITC, clone: mT2.7, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 11-9022-80
Additional Details : Weight : 0.25000kg
DescriptionDescription: The mT2.7 monoclonal antibody reacts with mouse Toll-like receptor 2 (TLR2). Mouse TLR2 is expressed by the myeloid lineage, including macrophage and dendritic cells in splenocytes and the RAW264.7 cell line. To date, at least twelve members of the Toll family have been identified in human and mouse. This family of type I transmembrane protein is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR2 is expressed on the surface of cells and is responsible for distinguishing different pathogens.Applications Reported: This mT2.7 antibody has been reported for use in flow cytometric analysis.Applications Tested: The mT2.7 antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
|PBS with 0.09% sodium azide; pH 7.2|
|TIL4, Toll-like Receptor 2, toll/interleukin 1 receptor-like 4, toll/interleukin-1 receptor-like protein 4|
|IgG2a, kappa, kappa|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.