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CD307e (FcRL5) Monoclonal Antibody (509F6), eFluor™ 660, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 50-3078-42

2330.11 SEK valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.23750kg

Product Code. 15579926

  • 3495.00 SEK / 100 tests
Estimated Shipment: 07-05-2024
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Description

Description

Description: The 509F6 monoclonal antibody reacts with human CD307e which is also known as Fc receptor-like 5, FcRL5, FcRH5, or IRTA2. CD307e is a surface protein expressed selectively on naive mature B cells and on bone marrow plasma cells, and binds to all IgG isotypes. CD307e functions as an inhibitory coreceptor on mature B cells in humans via the recruitment of the phosphatase SHP-1 to its two immunoreceptor tyrosine-based inhibitory motifs (ITIM). CD307e can also exist in soluble form and high levels of soluble CD307e have been detected in the blood of patients with multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma. Because surface-bound CD307e is also highly-expressed on maligt B cells from multiple myeloma, chronic lymphocytic leukemia, and mantle cell lymphoma patients, CD307e may be a useful therapeutic target for the treatment of these cancers. Applications Reported: This 509F6 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 509F6 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 μL (1 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. eFluor™ 660 is a replacement for Alexa Fluor™ 647.

CD307e (FcRL5) Monoclonal antibody specifically detects CD307e (FcRL5) in Human samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD307e (FcRL5)
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Q96RD9
FCRL5
Affinity chromatography
RUO
83416
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
509F6
eFluor 660
FCRL5
BXMAS1; BXMAS1-like protein 2; CD307; CD307e; fc receptor homolog 3; Fc receptor homolog 5; Fc receptor like 5; Fc receptor-like 3; Fc receptor-like 5; Fc receptor-like protein 3; Fc receptor-like protein 5; Fcrh3; FCRH5; Fcrl3; Fcrl5; FcR-like protein 5; Immune receptor translocation-associated protein 2; immunoglobulin superfamily receptor translocation associated 2 (IRTA2); IRTA2; mBXMH2; moFcRH3; PRO820; rCG62831-like; UNQ503/PRO820
Mouse
100 Tests
Primary
Human
Antibody
IgG2a κ
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