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CD314 (NKG2D) Monoclonal Antibody (CX5), Super Bright™ 600, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
1506.00 SEK - 3445.00 SEK
Specifications
Antigen | CD314 (NKG2D) |
---|---|
Clone | CX5 |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15933564
|
Affymetrix eBioscience
63-5882-82 |
100μg |
3445.00 SEK
100µg |
Estimated Shipment: 23-05-2024 Log in to see stock. |
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15923564
|
Invitrogen
63-5882-80 |
25 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The CX5 monoclonal antibody reacts with the mouse NKG2D, a lectin-like molecule expressed on both human and mouse NK cells. Mouse NKG2D binds to retinoic acid-inducible RAE-1 alpha, beta, gamma, delta, epsilon and the minor histocompatibility molecule H60 and has the ability to costimulate multiple NK activation receptors, through the DAP12/DAP10 adaptor molecules. NKG2D is expressed by all spleen and liver NK cells, NK1.1^+ thymocytes, in vitro activated LAK cells, and a subset of splenic NKT cells. Applications Reported: This CX5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This CX5 antibody has been tested by flow cytometric analysis of mouse splenocytes. This may be used at less than or equal to 1.0 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Super Bright 600 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 600 nm. We recommend using a 610/20 bandpass filter. Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (Product No.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells can regulate specific humoral and cell-mediated immunity, and preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NK gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.Specifications
CD314 (NKG2D) | |
0.2 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
O54709 | |
Klrk1 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Klrk1 |
CX5 | |
Flow Cytometry | |
Super Bright 600 | |
Rat | |
Mouse | |
27007 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |