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CD314 (NKG2D) Mouse anti-Human, Clone: 1D11, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-5878-82

Additional Details : Weight : 0.01000kg

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Product Code. 15207547

  • 1810.00 SEK / 100µg


Estimated Shipment
03-12-2020
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Description

Description

Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.
Specifications

Specifications

CD314 (NKG2D)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P26718
CD314, NK cell receptor D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, killer cell lectin-like receptor subfamily K member 1
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation, Neutralization
1D11
Unconjugated
KLRK1
Liquid
KLRK1
IgG1, kappa
100 μg
4° C
Primary
22914
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SDS
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For Research Use Only.