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CD32 Monoclonal Antibody (6C4 (CD32)), Functional Grade, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
1224.00 SEK - 3915.00 SEK
Specifications
Antigen | CD32 |
---|---|
Clone | 6C4 (CD32) |
Concentration | 1 mg/mL |
Applications | Flow Cytometry, Functional Assay |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15268427
|
Affymetrix eBioscience
16-0329-81 |
50 μg |
1224.00 SEK
50µg |
In Stock Log in to see stock. |
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15278427
|
Affymetrix eBioscience
16-0329-85 |
500 μg |
3915.00 SEK
500µg |
Estimated Shipment: 06-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Description: This 6C4 monoclonal antibody reacts with human CD32 (also known as Fc gammaRII). This antibody recognizes two isoforms of the receptor, Fc gammaRIIA and Fc gammaRIIB. These 40-kDa polymorphic transmembrane glycoproteins are expressed on B cells, granulocytes, monocytes, macrophages, and platelets. Moreover, these receptors are detected on natural killer cells. CD32 enables interaction between Fc gammaRII-expressing cells and opsonized antigen or IgG-containing immune complexes. Both receptors exhibit low affinity towards IgG and play a role in inflammation and autoimmune disease. This clone has been reported to inhibit Ig binding in a rosette blocking assay. Applications Tested: This 6C4 (CD32) antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.
This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.Specifications
CD32 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with no preservative; pH 7.2 | |
CD32; CD32 receptor 2; CD32 receptor 2a; CD32A; CD32B; CD32C; CDW32; Fc fragment of IgG receptor IIa; Fc fragment of IgG receptor IIb; Fc fragment of IgG receptor IIc (gene/pseudogene); Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIa, receptor (CD32); Fc fragment of IgG, low affinity IIa, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32); Fc fragment of IgG, low affinity IIc, receptor for (CD32); Fc gamma receptor II; Fc gamma receptor IIa; Fc gamma receptor IIb; Fc gamma receptor IIC; Fc gamma RIIb; FCG2; Fc-gamma receptor II; fc-gamma RII; Fc-gamma RII-a; fc-gamma RII-b; Fc-gamma RII-c; fc-gamma-RIIa; Fc-gamma-RIIb; fc-gamma-RIIc; Fc-gamma-RII-D; FcGR; FCGR2; FCGR2A; FCGR2A1; FCGR2B; FCGR2C; fcRII; fcRII-a; fcRII-b; FCRIIC; FGFR2B; IGFR2; IgG Fc fragment receptor; IgG Fc gamma receptor II; igG Fc receptor II; IgG Fc receptor II-a; igG Fc receptor II-b; Ig | |
FCGR2A, FCGR2B, FCGR2C | |
Primary | |
4° C |
6C4 (CD32) | |
Flow Cytometry, Functional Assay | |
Functional Grade | |
Mouse | |
Human | |
P12318, P31994, P31995 | |
2212, 2213, 9103 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.