CD326 (EpCAM) Mouse anti-Human, Alexa Fluor 488, Clone: MH99, eBioscience™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 53-8326-42
Additional Details : Weight : 0.23750kg
DescriptionThe monoclonal antibody MH99 recognizes human CD326 also known as EpCAM (Epithelial cell adhesion molecule). This 40kDa type I transmembrane protein is involved in cell-cell interactions in a calcium-independent manner. EpCAM is expressed primarily on the basolateral surface of most epithelia. Although normal epithelia express low levels of CD326, increased expression has been correlated with increased proliferation and progression to a mesenchymal phenotype. CD326 has also been used as a diagnostic marker on circulating metastatic carcinoma cells, while cancer cells of non-epithelial origin do not express EpCAM.
Based on crossblocking studies, MH99 and 1B7 see overlapping epitopes.
|Alexa Fluor 488|
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|
|Epithelial cell adhesion molecule, KSA, TROP1|