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CD335 (NKp46) Monoclonal Antibody (9E2), Super Bright™ 600, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 63-3359-42
Additional Details : Weight : 0.01000kg
Description
Description: This 9E2 monoclonal antibody reacts with human CD335, which is also known as NKp46. Expressed on NK cells, CD335 is a member of the natural cytotoxicity receptor family that also includes NKp30 and NKp44. This type I transmembrane glycoprotein is involved in activating and expanding resting NK cells following interaction with dendritic cells to eliminate tumor and virus-infected (e.g., influenza) cells. CD335 also interacts with pancreatic beta cells during the development of type I diabetes. The 9E2 antibody has been reported to induce cytotoxicity. Applications Reported: This 9E2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 9E2 antibody has been pre-titrated and tested by flow cytometric analysis of normal human periheral blood cells. This can be used at 5 μL (0.03 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Super Bright 600 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 600 nm. We recommend using a 610/20 bandpass filter. Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (cat.
NKp46 (CD335, NCR1, ) is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. NKp46 consists of two Ig-like domains assembled to leukocyte immunoglobulin-like (LIR) and killer inhibitory receptors (KIR).Specifications
| CD335 (NKp46) | |
| Monoclonal | |
| 5 μL/Test | |
| PBS with BSA and 0.09% sodium azide; pH 7.2 | |
| O76036 | |
| NCR1 | |
| Affinity chromatography | |
| RUO | |
| 9437 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
| Flow Cytometry | |
| 9E2 | |
| Super Bright 600 | |
| NCR1 | |
| 1-Mar; activating receptor 1; Ar1; CD335; hNKp46; Kilr1; KILR-1; LY94; Ly-94; lymphocyte antigen 94; Lymphocyte antigen 94 homolog; lymphocyte antigen 94 homolog (activating NK-receptor; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); mAR-1; MAR1 (mouse activating receptor 1); mNKp46; natural cytotoxicity triggering receptor 1; Natural killer cell p46-related protein; natural killer cell receptor; Ncr1; NK cell-activating receptor; NK receptor KILR-1; NKACTR; Nkp46; NK-p46; NK-p46); rAR-1; rat-activating receptor 1 | |
| Mouse | |
| 100 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 κ |
For Research Use Only