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CD36/GPIIIb/GPIV Ab-3 Mouse Monoclonal Antibody, Epredia™

Ensure accurate, reproducible results in immunohistochemistry , immunofluorescence, flow cytometry and function blocking experiment.

1122.00 SEK - 4656.30 SEK

Specifications

Antigen CD36/GPIIIb/GPIV Ab-3
Clone 185-1G2
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Conjugate Unconjugated
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Products 5
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12602267
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MS-756-P0
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12612267
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MS-756-P1
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12692257
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MS-756-P
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MS-756-PABX
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Description

Description

CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischaemia observed in sickle cell disease and cerebral malaria. Ab-3 blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.

Host Species: Mouse

Clone: 185-1G2

Isotype: IgG2a/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Stimulated human leukocytes

Molecular Weight: 88 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Frozen only)
  • Western Blotting (Not suitable)
  • Immunofluorescence
  • Flow Cytometry
  • Function Blocking

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

CD36/GPIIIb/GPIV Ab-3
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen)
Unconjugated
Mouse
Hematopoietic
Stimulated human leukocytes
Primary
185-1G2
Monoclonal
Concentrated
RUO
Human
IgG2a κ
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