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CD365 (TIM1), Biotin, clone: RMT1-4, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-5861-85

Additional Details : Weight : 0.25000kg

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Product Code. 15229879

  • 2995.00 SEK / 500µg


Estimated Shipment date
from Supplier 26-09-2018
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Description

Description

Description: The RMT1-4 monoclonal antibody reacts with mouse CD365 (also known as TIM1 and HAVCR1) and is a member of the T cell immunoglobulin domain, mucin-like domain (TIM) gene family. CD365 has been found on activated CD4+ T cells, mast cells, and a subset of B cells. CD365 is involved in renal injury, tissue homeostasis, and T cell costimulation. CD365 promotes the differentiation of Th2 cells and the production of IL-4. CD365 can bind several ligands, including Hepatitis A virus, phosphatidylserine, TIM4, IgA, as well as itself. CD365 and TIM4 can mediate uptake of apoptotic cells through recognition of phosphatidylserine. CD365, as well as the other TIM family members, are associated with susceptibility to atopic and autoimmune diseases. In humans, certain polymorphic variants of CD365 are strongly associated with protection against atopy, and this association occurs only in individuals who have had past infection with hepatitis A virus (HAV).Applications Reported: This RMT1-4 antibody has been reported for use in flow cytometric analysis.Applications Tested: This RMT1-4 antibody has been tested by flow cytometric analysis of mouse CD365 (TIM1) transfected cells. This can be used at less than or equal to 0.5 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD365 (TIM1)
Monoclonal
0.5mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q5QNS5
HAVCR1, TIM-1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
RMT1-4
Biotin
Havcr1
Liquid
Havcr1
IgG2b, kappa, kappa
500μg
4° C, store in dark, DO NOT FREEZE!
Primary
171283
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