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CD366 (TIM3) Monoclonal Antibody (F38-2E2), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
1350.00 SEK - 3470.00 SEK
Specifications
Antigen | CD366 (TIM3) |
---|---|
Clone | F38-2E2 |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15568076
|
Affymetrix eBioscience
17-3109-41 |
25 Tests |
1350.00 SEK
25 tests |
Estimated Shipment: 27-03-2024 Log in to see stock. |
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15532696
|
Affymetrix eBioscience
17-3109-42 |
100 Tests |
3470.00 SEK
100 tests |
In Stock Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
Description: This F38-2E2 monoclonal antibody reacts with human CD366, also known as T cell immunoglobulin and mucin domain-containing protein 3 (TIM3) or HAVCR2. This cell surface receptor is expressed on activated CD4+ T cell subsets (e.g. Th1, Th17, and Treg), CD8+ T cells, monocytes, dendritic cells, and mast cells. Due to alternative splicing, CD366 exists as membrane-bound and soluble forms. Galectin-9 has been identified as the ligand for CD366. In humans, this receptor negatively regulates CD4+ T cells, influencing the secretion of some Th1- and Th17-related cytokines. CD366 has also been implicated in tolerance, autoimmune disease (e.g. multiple sclerosis), and HIV infection. Applications Reported: This F38-2E2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This F38-2E2 antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5 µL (0.06 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.
CD366 (TIM3) Monoclonal antibody specifically detects CD366 (TIM3) in Human samples. It is validated for Flow Cytometry.Specifications
CD366 (TIM3) | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2 | |
CD366; FLJ14428; Havcr2; HAVcr-2; Hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; kidney injury molecule-3; KIM-3; sCD366; soluble CD366; soluble TIM 3; T cell immunoglobulin mucin 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain containing 3; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin family member 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; Tim3; TIM-3; TIMD3; TIMD-3 | |
Havcr2 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
Havcr2 |
F38-2E2 | |
Flow Cytometry | |
APC | |
Mouse | |
Human | |
Q8TDQ0 | |
84868 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
For Research Use Only.