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CD366 (TIM3), FITC, clone: F38-2E2, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 11-3109-41

Additional Details : Weight : 0.23750kg

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Product Code. 15506526

  • 1040.00 SEK / 25 tests


Estimated Shipment date
from Supplier 25-07-2018
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Description

Description

Description: This F38-2E2 monoclonal antibody reacts with human CD366, also known as T cell immunoglobulin and mucin domain-containing protein 3 (TIM3) or HAVCR2. This cell surface receptor is expressed on activated CD4+ T cell subsets (e.g. Th1, Th17, and Treg), CD8+ T cells, monocytes, dendritic cells, and mast cells. Due to alternative splicing, CD366 exists as membrane-bound and soluble forms. Galectin-9 has been identified as the ligand for CD366. In humans, this receptor negatively regulates CD4+ T cells, influencing the secretion of some Th1- and Th17-related cytokines. CD366 has also been implicated in tolerance, autoimmune disease (e.g. multiple sclerosis), and HIV infection.Applications Reported: This F38-2E2 antibody has been reported for use in flow cytometric analysis.Applications Tested: This F38-2E2 antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5μL (0.125μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD366 (TIM3)
Monoclonal
5μl/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q8TDQ0
HAVCR2,TIM-3
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
F38-2E2
FITC
HAVCR2
Conjugated
HAVCR2
IgG1, kappa
25 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary
84868
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