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CD369 (Clec7a, Dectin-1) Rat anti-Mouse, APC, Clone: bg1fpj, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 17-5859-82

Additional Details : Weight : 0.09500kg

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Product Code. 15558146

  • 2685.00 SEK / 100µg


Estimated Shipment
04-01-2021
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Description

Description

It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered. CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predomitly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.
Specifications

Specifications

CD369 (Clec7A, Dectin-1)
Monoclonal
0.2 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
Q6QLQ4
UNQ539/PRO1082, BGR, CANDF4, CLECSF12, DECTIN1,C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; beta-glucan receptor; dectin-1; dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry
bg1fpj
APC
Clec7a
Liquid
Clec7a
IgG2a, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
56644
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For Research Use Only.