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CD369 (Clec7a, Dectin-1) Monoclonal Antibody (bg1fpj), PerCP-eFluor™ 710, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 46-5859-82
Additional Details : Weight : 0.09500kg
Description
CLEC7A, also known as dectin-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily and is predominantly expressed on myeloid cells. It is a small glycoprotein type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif (ITAM). CLEC7A functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Upon fungal exposure, CLEC7A activates Syk tyrosine kinase, triggering a massive oxidative burst through the formation of reactive oxygen species.
CD369 (Clec7a, Dectin-1) Monoclonal antibody specifically detects CD369 (Clec7a, Dectin-1) in Mouse samples. It is validated for Flow Cytometry.Specifications
| CD369 (Clec7a, Dectin-1) | |
| Monoclonal | |
| 0.2 mg/mL | |
| PBS with 0.09% sodium azide; pH 7.2 | |
| Q6QLQ4 | |
| Clec7a | |
| Baculovirus-expressed Fc-containing protein | |
| 100 μg | |
| Primary | |
| Mouse | |
| Antibody | |
| IgG2a κ |
| Flow Cytometry | |
| bg1fpj | |
| PerCP-eFluor 710 | |
| Clec7a | |
| Beta-glucan receptor; beta-GR; BGR; CANDF4; CD369; CLEC7A; Clec7b; CLECSF12; C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12; C-type lectin domain family 7 member A; C-type lectin domain family 7, member A; C-type lectin superfamily member 12; DC-associated C-type lectin 1; DECTIN1; dectin-1; Dendritic cell-associated C-type lectin 1; dendritic cell-associated C-type lectin-1; lectin-like receptor 1; RGD1565140; SCARE2; UNQ539/PRO1082 | |
| Rat | |
| Affinity chromatography | |
| RUO | |
| 56644 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
For Research Use Only.